for Premature Ejaculation



Sertraline is the active ingredient in Zoloft. Sertraline is a selective serotonin re-uptake inhibitor (SSRI) that helps increase the serotonin levels in your brain. 

Because serotonin is part of how your brain processes sexual excitement, SSRIs like Sertraline can help manage premature ejaculation, without numbing the penis, like delay wipes and sprays.


Sertraline for P.E. is taken daily. Simply take the medication at the same time every day, with or without food. Take Sertraline exactly as prescribed by a doctor.

GET Sertraline ONLINE 


SuperPill provides prescriptions for Sertraline online, without in-person trips to a doctor’s office and pharmacy. Start your online medical visit with 3 easy steps: 

  1. Select your medication.
  2. Answer basic health questions.
  3. Complete checkout.


Prescription medicine for premature ejaculation, such as Sertraline, and topical products like delay wipes or sprays can help increase time to ejaculation–but work differently. 

Sertraline is a daily pill, so it might be a good fit for people worried about having to plan sex or stop in the middle of the action to use the Delay Wipe.  

Delay wipes or sprays work by numbing the penis, but can also be transferred to the partners genitals during sexual activity. So, a condom will be necessary in order to avoid this. This is why so many men prefer sertraline over delay wipe or sprays. 

Customer Reviews


Consult your doctor about any medications, supplements, or vitamins you may take in case of drug interactions with SSRIs. Also, please read all of the important safety information before you start Sertraline. Contact us if you are experiencing side effects that concern you or don’t go away. Click here for the most common side effects.

FAQs about Sertraline

What qualifies as premature ejaculation?

Premature ejaculation occurs when a man has an orgasm and ejaculates earlier during intercourse than he or his partner would like. It's a common problem, affecting 30% to 40% of men. Causes include physical problems, chemical imbalances and emotional/psychological factors. 

Source: Cleveland Clinic

What is the average time of premature ejaculation?

A study involving 500 couples found the average time for ejaculation was about 5-and-a-half minutes after starting sex. This time could be longer for men who have sex with men. International guidelines define premature ejaculation as regularly ejaculating within 1 minute of entering your partner.

Source: NHS (UK)

Why do you ask for ID and a completed health form?

For new customers only. Our U.S. licensed physician will need to review your health information to ensure it's right for you. And our U.S. certified pharmacy will need to verify your identity, in order to mail prescription medication. Your information is kept private and secure, as our servers are HIPAA compliant. For further details please read our Privacy, Telemedicine, or Terms & Conditions. This is a one-time requirement, so you won't need to do this when you place future orders.

Over the counter Sertraline cannot be sold legally in the US. Only buy from US-based clinics/pharmacies, with medical providers licensed to provide care in your state and are licensed to fulfill medications in your area. Avoid foreign online pharmacies, to ensure your medications are safe and you don't get scammed.

Is premature ejaculation forever?

However, men who have primary ejaculation who have suffered from the problem since becoming sexually active may likely be long-lasting. Luckily through the right treatment, men suffering from this type of PE have a good chance of improving or even resolving their condition.

Source: Priority Men's Medical Center

What off-label uses is sertraline prescribed for?

Sertraline is not FDA-approved for the treatment of premature ejaculation but is prescribed for off-label uses for issues like premature ejaculation. Learn more about 'off-label uses' click here.

How do you order premature ejaculation pills online?

Sertraline is a prescription medication, so in order to use sertraline to treat premature ejaculation, you will need to be evaluated by a doctor, who will determine if it’s appropriate for you. You can get connected to a doctor online through SuperPill.com platform by completing our health questionnaire. If our doctor determines sertraline is appropriate for you after the online visit, they can prescribe you Sertraline online and you can get it delivered to your door.

What can help with premature ejaculation without medication?

Here the most common techniques and treatments used to stop premature ejaculation:

The 'Stop-Start' Strategy: One of the oldest and most effective ways to stop premature ejaculation is through this method with your partner or by yourself. As you feel yourself approaching orgasm and ejaculation, stop the stimulation and take a break, then repeat until you feel more confident in your ability to control your ejaculation.

The 'Squeeze' Technique: During sex, as you’re approaching ejaculation, squeeze the area between the shaft and glans of the penis to prevent ejaculation. Most of the resources on the squeeze technique recommend squeezing the penis for about 30 seconds to stop premature ejaculation. Since everyone is different, the ideal amount of time for the technique might be slightly shorter or longer. Using the squeeze technique, you can delay orgasm several times, allowing yourself to perform for longer during sex. Like the stop-start technique, the squeeze technique has its downsides. First, it results in a stop in sexual activity, which can be frustrating for both you and your partner. It can also occasionally reduce the intensity of your erection, which also affects sexual enjoyment.

Masturbating before sex: While there’s no scientific evidence to support this method, many men find that masturbation shortly before sex is an effective way to delay orgasm and stop premature ejaculation. The idea behind this approach is that during the refractory period (a recovery phase that occurs after orgasm), most men won’t be able to orgasm again. The end result is a longer average time to orgasm and, for their partners, better sexual satisfaction.

Selective Serotonin Reuptake Inhibitors (SSRIs): Right now, there aren’t any medications specifically approved to treat PE. However, there are a variety of existing drugs -- particularly medications commonly used to treat depression and anxiety disorders -- that have been shown in clinical practice to be effective in helping men delay orgasm and ejaculation. SSRIs are prescription medication, meaning you’ll need to speak with a doctor about this PE treatment method. Most medications in this class also have side effects, which you’ll want to discuss with your doctor prior to considering treatment.

Gels, Creams and other topical treatments: Most gels and sprays use local anesthetics such as lidocaine -- the same anesthetic that’s used by dentists and laser hair removal technicians. Studies show that this topical anesthetic combination is fairly effective. However, topical treatments like lidocaine/prilocaine cream may have a downside. Because they numb the penis and reduce sensation (for both parties), they might contribute to erectile loss–a symptom noted by more than 50% of the men that received the cream in a 2002 study.

You may also like... 

Sale Off


Sale Off


Sale Off
Finasteride for Hair Loss

Finasteride for Hair Loss